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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79374 | NMDA receptor antagonist 7 | iGluR | |
Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM. It is potentially useful for research into neurodegenerative diseases [1]. | |||
T10191L | 7-Chlorokynurenic acid | 7-chloro-4-hydroxy-2-carboxyquinoline,7-CKA | GluR , NMDAR |
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake... | |||
T8435 | YM90K | YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)- | GluR , iGluR |
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor. | |||
T71760 | 4-Chlorokynurenine | ||
4-Chlorokynurenine is a prodrug of 7-Cl-kynurenic acid (7-Cl-KYNA), a potent, selective antagonist of the NMDA/glycine receptor. | |||
T10191 | 7-Chlorokynurenic acid sodium salt | 7-CKA sodium salt | Others |
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM). It is also a potent inhibitor of the reuptake of glutamate... | |||
T22048 | Bis(7)-Tacrine | ||
Bis(7)-tacrine dihydrochloride is a dimeric AChE inhibitor derived from tacrine with a potential to treat Alzheimer's disease. Bis(7)-tacrine dihydrochloride prevents glutamate-induced neuronal apoptosis by blocking NMDA... | |||
T27269 | Ensaculin HCl | KA 672,KA672,Ensaculin,Anseculin Hydrochloride,KA-672 HCl | |
Ensaculin is a NMDA antagonist and a 5HT1A agonist potentially for the treatment of Alzheimer's disease (AD). Ensaculin showed memory-enhancing effects in paradigms of passive and conditioned avoidance in both normal and... |